• Welcome to Action Project's Website

    ACTION is a collaborative project among twelve international partners, which has been selected by the European Commission as one of the projects funded under the 7th Framework Programme for Research, technological Development and Demonstration.
    The project is funded under the sub-programme HEALTH.2013.2.2.1-3: "Paediatric conduct disorders characterised by aggressive traits and/or social impairment: from preclinical research to treatment".

  • ACTION's main objectives

    ACTION aims to improve the understanding of the causes of individual differences in aggression among children in order to better inform the development of prevention and treatment strategies. The project will investigate current and diagnostic problems in paediatric aggression, including the differential expression of aggression as a function of gender, developmental stage, and patterns of comorbidity. It will reveal predictive outcome of childhood aggression by examining longitudinal trajectories in large scale longitudinal data.

  • Genetic and Metabolomic approaches

    ACTION will quantify the influences of genes and environment as a function of gender, age, birth cohort, and environmental modifiers; it will identify genomic regions of interest for aggression by means of a genome-wide association (GWA) studies;ACTION will apply and develop new methods to study gene-environment correlation and interaction by including measured genes and measured environment; it will select informative groups of children for inclusion in epigenetic and metabolomic biomarkers studies of paediatric aggression.

  • Aggression in identical twins

    One of the ACTION's goals is to improve the understanding of the causes of individual differences in aggression among twins in order to better inform the development of prevention and treatment strategies. ACTION will combine twin samples and metabolomic biomarker data to establish direction of causation. As Yin and Yang are both complementary and opposite, also monozygotic twins have the same genetic heritage but can have different environmental influences that can make them distinguished: same genome but different epigenome, metabolome, phenome and diseasome.

  • Consortium

Last event

The Early Career Scientists Workshop on Aggression was a joint event organised by three european projects (ACTION, Aggressotype and Matrics) and dedicated to early career scientists from any of the three consortia. It took place in Nijmegen, The Netherlands, October 31, November 01. ACTION presentations available in this page.

Last media

ACTION has been presented during the 12th International Workshop on Neonatology, Cagliari, Italy, October 19-22, 2016.